

Optometry and Visual Neuroscience Laboratory
Optometry Department
National School of Higher Education, Leon Unit-UNAM


At @VisNeuroscLab (neur-opht-research.com) you can explore the realms of ophthalmological, optometry, and neuroscience research, where knowledge meets innovation. Discover a range of services catering to both professionals and the public, including cutting-edge programs and social initiatives. Proudly affiliated with the ENES, UNIDAD LEÓN, UNAM, our institution is committed to advancing science, promoting eye health, and fostering community well-being
Research areas

BASIC
The basic research is focused on developing knowledge as well as providing solutions to various eye diseases that affect the Mexican population.
CLINIC
Our research laboratory and the Optometry Clinic participates continuously developing clinical research protocols
Research on:
-Age-Related Macular Degeneration
-Diabetic Retinopathy
-Macular Diabetic Edema
-Aging
-Alzheimer´s Disease Early Diagnosis
-Metabolic and Transcriptomic analysis in Diabetic Retinopathy
Our Team.
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A Sight to See





Corneal alkali burn model for evaluation of anti-inflammatory compounds

Our Services
Our latest publications
Rodríguez-Arzate, C. A., Noguez-Imm, R., Reyes-Ortega, P., Rodríguez-Ortiz, L. R., García-Peña, M. F., Ordaz, R. P., ... & Thébault, S. C. (2024). Potential contributions of the intrinsic retinal oscillations recording using non-invasive electroretinogram to bioelectronics. Frontiers in Cellular Neuroscience, 17, 1224558.
Hernández, E. R., Zimbrón, L. F. H., Pérez, E. S., Salgado, J. L. S., Morales, M. A. P., & Zenteno, E. (2024). Galectin-9 and Tim-3 are upregulated in response to microglial activation induced by the peptide Amyloid-β (25–35). Neuropeptides, 102426.ed Tech
Salazar-Gómez, A., Velo-Silvestre, A. A., Alonso-Castro, A. J., & Hernández-Zimbrón, L. F. (2023). Medicinal plants used for eye conditions in mexico—A review. Pharmaceuticals, 16(10), 1432.
"A novel and functional Artificial Bruch's Membrane made of Poly (ε-caprolactone)/Gelatin for Retinal Pigment Epithelium Restoration" (has been accepted for publication.)
Noguez Imm, R., Muñoz-Benitez, J., Medina, D., Barcenas, E., Molero-Castillo, G., Reyes-Ortega, P., ... & Thébault, S. C. (2023). Preventable risk factors for type 2 diabetes can be detected using noninvasive spontaneous electroretinogram signals. PLoS One, 18(1), e0278388.
ONGOING STUDENT RESEARCH PROJECTS
1. Análisis del grosor macular central, nivel lipídico y glucémico, agudeza visual y respuesta en electrorretinograma en pacientes sanos, prediabéticos, con síndrome metabólico y diabéticos
2. Contaminación por partículas de aire, neurotoxicidad y diabetes: efectos y mecanismos para los riesgos en salud visual en el sector ladrillero
3. Estudio de la correlación entre el perfil metabolómico sérico, las señales del electrorretinograma basal y la expresión génica en personas con riesgo de desarrollar diabetes tipo 2: impacto de la actividad física.
4. Estudio del efecto de la savia de tres especies del género Sedum sobre la expresión de mediadores inflamatorios y su potencial uso en la prevención y tratamiento del síndrome del ojo seco.
5. Biomarcadores inflamatorios de segmento anterior en pacientes con diabetes
6. Detección de péptidos amiloides de la superficie ocular en pacientes con enfermedades neurodegenerativas.
7. Evaluación de percepción visual y visión al color en personas con enfermedades neurodegenerativas
8. Programa Institucional de Atención Integral No mas complicaciones con la diabetes
Facilities

CONTACT
Address
Blv. UNAM #2011, Predio El Saucillo y, Comunidad de los Tepetates, El Potrero, 37684 León, Gto
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